图书简介
The book deals wTh basic cellular and molecular mechanisms associTed wTh aging. T comprehensively describesThe impoTaT genTic, epigenTic, biochemical and mTabolic regulTions during aging, as well as some impoTaT age-relTed diseasesThe book is divided iTo four major seTions for easy underTanding. TTakesThe readersThroughThe various aspeTs of aging in a Tory-like manner. CeTain iTerveTions for heaThy aging such as diTary reTriTion, regular exercise and maiTaining a balanced and peaceful life-Tyle are also suggeTed byThe expeTs.The book would be a companion for bTh beginners, as well as eTablished researchers inThe field. T would be useful for science educTion, research, clinical approach and policy making.
PART I ~ ALTERATIONS INCELLULAR MCHANISMS DURING AGING.-Chapter 1Protein StrCture and FuCtion in Aging and Age-related Diseases.-Chapter 2DNA, DNA ReplCation and Aging.-Chapter 3TranCription and Aging.-Chapter 4Ribosomes, Translation and Aging.-Chapter 5p53 and Aging.-Chapter 6Paired Box (Pax) TranCription FCtors and Aging.-Chapter 7Telomeres, Telomerase and Aging.-Chapter 8The Epigenome of Ageing.-Chapter 9Attaining EpigenetC Rejuvenation:Challenges Ahead.-Chapter 10MitChondria as a Key Player in Aging.-Chapter 11Aging, Free RadCals and ReCtive Oxygen SpCies: An EvolvingCoCept.-Chapter 12StemCells and Aging.-Chapter 1Can Autophagy Stop theClCk: Unravelling the Mystery in DCtyostelium diCoideum.-Chapter 14Aging: Reading, Reasoning and Resolving Using Drosophila as a Model System.-Chapter 15NothobraChius furzeri as a New Model System for Aging Studies.- PART IIALTERATIONS IN METABOLISM DURING AGING AND DISEASES.-Chapter 16Aging in MuCle.-Chapter 17MetabolC Diseases and Aging.-Chapter 18Interplay Between Nutrient Sensing MolCules During Aging and Longevity.-Chapter 19Protein Aggregation, Related Pathologies and Aging.-Chapter 20BiologCal Rhythms and Aging.-Chapter 21The Biology of Ageing andCaCer – AComplex AssCiation.
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